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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
22.12
Human Site:
Y507
Identified Species:
37.44
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
Y507
S
D
V
H
L
N
F
Y
V
Y
Y
G
P
D
R
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
Y507
S
D
V
H
L
N
F
Y
V
Y
Y
G
P
D
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
Y604
S
D
V
H
L
N
F
Y
V
Y
Y
G
P
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
Y501
S
E
V
H
L
N
F
Y
V
Y
Y
G
P
D
R
Rat
Rattus norvegicus
NP_001099948
974
110023
Y472
S
E
V
D
L
N
L
Y
V
Y
Y
G
P
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
G462
E
R
R
W
I
L
T
G
T
P
I
Q
N
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
Y497
P
E
V
H
L
N
I
Y
I
Y
Y
G
P
E
R
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
H487
N
K
A
S
S
P
L
H
N
V
K
W
L
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
C555
S
R
Q
K
L
T
V
C
V
H
H
G
N
N
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
C583
D
E
L
Q
V
N
V
C
L
Y
Y
G
A
E
K
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
N377
S
R
A
V
T
K
L
N
A
K
R
R
W
V
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
S459
V
V
C
K
L
K
A
S
R
R
W
A
V
T
G
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
L368
M
Y
S
L
I
R
F
L
N
I
N
P
F
T
K
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
M665
E
G
T
F
K
T
M
M
Y
Y
G
A
E
K
N
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
80
N.A.
0
N.A.
66.6
0
N.A.
33.3
N.A.
N.A.
26.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
86.6
N.A.
6.6
N.A.
86.6
13.3
N.A.
53.3
N.A.
N.A.
66.6
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
6.6
N.A.
N.A.
13.3
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
0
8
0
8
0
0
15
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
15
0
0
0
0
0
0
0
% C
% Asp:
8
22
0
8
0
0
0
0
0
0
0
0
0
36
0
% D
% Glu:
15
29
0
0
0
0
0
0
0
0
0
0
8
15
0
% E
% Phe:
0
0
0
8
0
0
36
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
8
58
0
0
8
% G
% His:
0
0
0
36
0
0
0
8
0
8
8
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
8
0
8
8
8
0
0
0
0
% I
% Lys:
0
8
0
15
8
15
0
0
0
8
8
0
0
8
15
% K
% Leu:
0
0
8
8
58
8
22
8
8
0
0
0
8
0
8
% L
% Met:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
50
0
8
15
0
8
0
15
8
8
% N
% Pro:
8
0
0
0
0
8
0
0
0
8
0
8
43
0
0
% P
% Gln:
0
0
8
8
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
22
8
0
0
8
0
0
8
8
8
8
0
8
50
% R
% Ser:
50
0
8
8
8
0
0
8
0
0
0
0
0
8
0
% S
% Thr:
0
0
8
0
8
15
8
0
8
0
0
0
0
15
0
% T
% Val:
8
8
43
8
8
0
15
0
43
8
0
0
8
8
15
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
8
8
8
0
0
% W
% Tyr:
0
8
0
0
0
0
0
43
8
58
50
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _